Current Advances in Hydroxyapatite- and ?-Tricalcium Phosphate-Based Composites for Biomedical Applications: A Review

This review focuses on the advances made in synthesis and application of hydroxyapatite (HA)- ?-tricalcium phosphate (?-TCP)-based composites for biomedical purposes, with placed both laboratory exploration clinical translation. First, polymeric matrix materials are reviewed, comparisons between naturally- synthetically-derived polymers briefly introduced. Second, calcium phosphates used hard tissue replacement broadly primary distinctions HA ?-TCP discussed. A wide range HA- ?-TCP-polymer various applications then reviewed extensively, biological mechanical properties emphasized, along fabrication methods that have been developed. Finally, clinically implemented surveyed, commercially available products their respective uses highlighted.